This is an abstract of a survey1 to which the reader is referred for detailed statistical data, prepared from the case histories collected from the five cooperating clinics2 and assembled for statistical study with the cooperation of the United States Public Health Service. This is the first of a series of reports to be published by this group on the various manifestations of neurosyphilis, the treatment and the end-results.
Asymptomatic neurosyphilis is the type of neurosyphilis which is characterized by a positive reaction of the spinal fluid but in which there are neither objective nor subjective symptoms of involvement of the central nervous system. Asymptomatic neurosyphilis may be demonstrated during either the early or the late stages of syphilis, and it may occur in association with other manifestations of syphilis in the cardiovascular system, liver or skin. The asymptomatic form of neurosyphilis is a highly
O'LEARY PA, COLE HN, MOORE JE, STOKES JH, WILE UJ, PARRAN T, VONDERLEHR RA, USILTON LJ. COOPERATIVE CLINICAL STUDIES IN THE TREATMENT OF SYPHILIS: ASYMPTOMATIC NEUROSYPHILIS. Arch Derm Syphilol. 1937;35(3):387–401. doi:10.1001/archderm.1937.01470210013002