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A Case for Diagnosis (Syphilis?) in the Third Generation. Presented by Dr. Fred Wise.
P. L., aged 3½ years, a well developed and well nourished girl, in the care of Dr. Rein and Dr. Shostac, presents no clinical stigmas of congenital syphilis. The reaction of her blood was strongly positive on repeated Kline, Kahn and Wassermann tests. Her mother, aged 24, presents no clinical evidence of syphilis; Kline, Kahn and Wassermann tests of her blood gave strongly positive reactions. The patient's father shows no clinical or serologic evidence of syphilis. Two maternal aunts, aged 30 and 26, respectively, had negative serologic reactions, while two maternal uncles, aged 21 and 17, respectively, had positive serologic reactions. One maternal uncle (L. C.), aged 15, shows no clinical or serologic evidence of the disease. The patient's maternal grandmother, aged 54, first reported to her physician in 1921 complaining of nervousness. She received at
Parounagian MB, Bechet PE. MANHATTAN DERMATOLOGIC SOCIETY. Arch Derm Syphilol. 1937;35(5):992–994. doi:10.1001/archderm.1937.01470230230015