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Pachyonychia Congenita. Presented by Dr. Botho Friedrich-Wilhelm Felden.
I. L., a boy aged 14, is presented from the Skin and Cancer Unit of the New York Post-Graduate Medical School and Hospital because of a condition which has been present for seven years. On both feet are various-sized sharply outlined erythematous patches with bullous lesions. The toe nails are absent. The finger nails are discolored, brittle and deformed. Some of them are thickened. Follicular keratosis involves the elbows, the knees and the face. The edges of the tongue show leukoplakia. Examination of the nails for tinea and tests with oidiomycin and trichophytin gave negative results.
Dr. G. F. Machacek: This patient was under treatment for a number of years at the Vanderbilt Clinic, and I believe he had his toe nails removed a few years ago. They were enormously thick.Dr. Botho Friedrich-Wilhelm Felden: This boy told me that all
Chargin L, Saunders HC. NEW YORK ACADEMY OF MEDICINE, SECTION OF DERMATOLOGY AND SYPHILIS. Arch Derm Syphilol. 1938;37(6):1078–1092. doi:10.1001/archderm.1938.01480120144024