The desirability of a serologic test for syphilis more rapid and more easily performed than any at present available at the Massachusetts General Hospital, to be used in the outpatient clinic and for the testing of emergency donors, gave the incentive for a comparative study of the Laughlen test with the tests now in use, i. e., the Hinton, the Wassermann and the Kahn.
The Hinton test is used as a routine at the Massachusetts General Hospital on all specimens of serum sent to the laboratory. The less sensitive standard Wassermann test rather than the Kolmer modification is performed on the serums giving a positive Hinton reaction, in order to grade the more strongly positive ones. The Kahn test is done in emergencies. The technics of these tests are too well known to require description. In the present study the rapid Hinton method was used in 780 cases. This test
LEVER WF, MASSIE WK. THE LAUGHLEN TESTIN THE DIAGNOSIS OF SYPHILIS. Arch Derm Syphilol. 1939;40(1):45–52. doi:10.1001/archderm.1939.01490010048006