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To the Editor:—
The case reported by Drs. E. W. Netherton and G. D. Curtis (A Case for Diagnosis [Erythema Perstans? Fixed Drug Eruption?], Arch. Dermat. & Syph. 40:330 [Aug.] 1939) at the Dec. 15, 1938, meeting of the Cleveland Dermatological Society, raised various questions that I should like to answer.Dr. Henry A. Brunsting, of Toledo, Ohio, stated in referring to phenolphthalein that "one type can be used sometimes without a flare-up while the other type causes difficulties." As Dr. Netherton indicated, either yellow or white phenolphthalein may cause a flare-up of the eruption. This has been p[ill]oved many times; so I think that there is no longer any doubt about it.In reference to the discussion of Dr. I. L. Schonberg regarding a phenolphthalein eruption from the eating of iced cup cakes, this was a report published by me (M. J. & Rec. 136:31 [July 6]
Abramowitz EW. FIXED DRUG ERUPTIONS. Arch Derm Syphilol. 1939;40(3):436. doi:10.1001/archderm.1939.01490030093015