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The appearance of the official Pharmacopeia of the United States XII, and the National Formulary VII (November 1942) warrants the presentation of a few items of interest to dermatologists.
The description of calamine and neocalamine from the official texts should remove for all time the ancient ideas regarding the character of these preparations. The early texts gave less simple definitions for the calamine of the pharmacy. Prior to 1914, there may have been some form of calamine available with special chemical characteristics. But the description of prepared calamine as "calcined zinc carbonate" really meant zinc oxide, for the process of calcining drove off the carbon dioxide and left the oxide form of the zinc. Whether calamine (prepared) or neocalamine (prepared) is utilized, the only ingredient is zinc oxide slightly and variously colored with some form of iron rust. The color of the neocalamine is a closer match to that of
GOODMAN H. CALAMINE AND NEOCALAMINE, 1942. Arch Derm Syphilol. 1943;48(4):369. doi:10.1001/archderm.1943.01510040013002