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Arsenoresistant Syphilis (Improved). Presented by Dr. Girsch D. Astrachan.
H. L., a man aged 31, was presented before this section on April 2, 1943 for diagnosis (arsenoresistant syphilis? pyogenic ulceration? destruction of nose?).
Since then the patient has received six injections of a bismuth preparation and seven of dichlormapharsen (dose 15 to 50 mg.), the latter given concurrently with crude liver extract. A striking improvement was noticed after five injections of the arsenical were given. Locally, dressings wet with solution of boric acid were applied for one to two hours daily.
Examination today shows the ulcerated areas on the cheeks and forehead healed, with smooth scars left. Otherwise the condition of the patient is the same as on April 2.
A culture for anaerobic organisms was made on February 10, and no growth was seen after seventy-two hours' incubation. The Wassermann and Kahn reactions of the blood were
Combes FC, Gross P. NEW YORK ACADEMY OF MEDICINE, SECTION OF DERMATOLOGY AND SYPHILIS. Arch Derm Syphilol. 1944;49(2):150–152. doi:10.1001/archderm.1944.01510080062019