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Von Recklinghausen's Disease in Mother, Forme Fruste Type in Son and Daughter. Presented by Dr. Maurice J. Costello.
E. B., a woman aged 35 (private patient), has had a typical eruption of von Recklinghausen's disease since she was 12 years old. She had meningitis at the age of 10 and osteomyelitis of the long bones for twelve years thereafter. In 1934 she had an abscess of the left kidney, and she has had two miscarriages. She has difficulty in hearing with the left ear. During the past year the patient complained of itching of lesions located on the head, back of the neck and upper part of the back.
Her son, J. W. B., aged 11, has the forme fruste type of von Recklinghausen's disease. He has a number of café-au-lait spots on the trunk, varying in size from 0.5 to 3 cm. There are a number of round
Schwartz HJ, Andrews GC. NEW YORK DERMATOLOGICAL SOCIETY. Arch Derm Syphilol. 1946;53(2):204–212. doi:10.1001/archderm.1946.01510310128017