DISCUSSION with dermatologists results in the opinion that the majority have been unable to arrive at a conclusion as to the value of treatment of acne with vitamin A or have judged it to be of little value in spite of the rather favorable report by Straumfjord.1 Published reports have been few and inconclusive. Experimental studies by Cornbleet and his associates2 failed to demonstrate any lack of vitamin A in the blood of patients with acne. Obermayer and Frost3 recently said that as yet they "are prepared only to state that vitamin A therapy is undoubtedly of benefit in the handling of some forms of acne vulgaris while others do not seem influenced by it."
In order to arrive at an opinion, we determined to observe the effects of vitamin A given orally in a dosage of 100,000 units daily to a group of university students with
LYNCH FW, COOK CD. ACNE VULGARIS TREATED WITH. VITAMIN A. Arch Derm Syphilol. 1947;55(3):355–357. doi:10.1001/archderm.1947.01520030048006