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Article
June 1948

TRIBROMOETHANOL ("AVERTIN") IN THE TREATMENT OF NEURODERMATOSES

Author Affiliations

PITTSBURGH

From the Department of Dermatology and the University of Pittsburgh School of Medicine.

Arch Derm Syphilol. 1948;57(6):1019-1027. doi:10.1001/archderm.1948.01520190098013
Abstract

IN MY experience, the accepted treatment for the management and treatment of neurodermatoses, consisting of topical applications, attention to the patients' general and nervous status, roentgen irradiation, sedation and psychotherapy, has produced satisfactor.y results in only a small percentage of the cases. The subsequent recurrence and ultimate failure of recognized treatment to relieve these patients prompted this study. This report, therefore, is concerned with the consideration of another therapeutic approach, the use of a basal anesthetic, solution of tribromoethanol ("avertin with amylene hydrate"), which is tribromoethyl alcohol (CH3CH2OH).

The use of anesthesia in the treatment of cutaneous disorders has been receiving considerable attention in the current literature. The principle is, however, not new. In the early part of the nineteenth century, sedation with opium and ether and chloroform by inhalation and rectal injection was employed in the treatment of mental illness. In the early part of

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