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Article
October 1948

EOSINOPHILIC GRANULOMA OF THE SKINReport of Three Cases

Author Affiliations

BOSTON

From the Departments of Dermatology, Massachusetts General Hospital and Boston City Hospital.

Arch Derm Syphilol. 1948;58(4):430-438. doi:10.1001/archderm.1948.01520230075009
Abstract

EOSINOPHILIC granuloma of the skin is a new and not yet well defined disease entity. Occasional case reports under this diagnosis have appeared in the European literature since 1937. In the United States the disease received little attention until 1946. Since then, however, five papers on this subject have been published,1 among them one from Boston.1d Nineteen cases in which the disease was diagnosed as eosinophilic granuloma of the skin are now recorded in the literature.

Three additional cases have recently been seen in Boston. The appearance in these cases, clinically as well as histologically, was almost identical with that in the first case reported from Boston.1d In fact, the clinical features of these 4 cases were so characteristic that in 1 instance (case 2) the diagnosis was made before biopsy.

REPORT OF CASES 

Case 1.—  A 52 year old man first noticed in 1942 a small

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