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Article
December 1948

STREPTOMYCIN OINTMENT IN TREATMENT OF SYCOSIS VULGARIS

Author Affiliations

HONOLULU, HAWAII

Arch Derm Syphilol. 1948;58(6):741. doi:10.1001/archderm.1948.01520250085010
Abstract

Several months ago a former patient wrote to me regarding the cure of his recalcitrant sycosis vulgaris. This condition had been refractory to all topical medications, including penicillin ointment, guinolor® ointment,1 ammoniated mercury ointment and wet dressings of tyrothricin. An ophthalmologist had casually mentioned that streptomycin ointment might be tried, as it had been successful in treatment of staphylococcic marginal blepharitis. In seven days the patient's skin was entirely clear, and it has remained so for six months at the time of writing.

An ointment containing 1,000,000 units of streptomycin powder per ounce (28 Gm.) of carbowax 1540® was used. This was vigorously applied before and after shaving and again at bedtime. Fifteen patients with sycosis vulgaris were treated. Duration of infection varied from two weeks to nine months. Cultures of infected hairs produced Staphylococcus aureus and Staphylococcus albus. In 12 cases there were good results, with clearing in

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