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Granuloma Inguinale Treated with Streptomycin. Presented by Dr. Theodore Rosenthal.
A. J., a Negro aged 39, was admitted to the Central Social Hygiene Clinic of the New York Department of Health on Dec. 5, 1947.
An indurated ulcer, 1 cm. in diameter, was situated on the corona of the penis. Donovan bodies were demonstrated in the lesion, which had been present for the past six weeks.
The patient was given streptomycin suspended in peanut oil and white wax U. S. P., each cubic centimeter containing 300,000 units. He received a total of 20 Gm. in a course of single daily intramuscular injections for twelve days, except Sundays. The lesion was completely healed on December 18, the date of the last injection, and has remained healed.
Repeated dark field examinations were negative for Treponema pallidum. The Wassermann reactions of the blood were negative on December 2 and 18 and on Jan.
Wolf C, Silver H. BRONX DERMATOLOGICAL SOCIETY. Arch Derm Syphilol. 1950;61(1):125–137. doi:10.1001/archderm.1950.01530080131023