BENEFICIAL effects from employing corticotropin (ACTH) have been reported in two patients with penicillin urticaria and in one with a severe exfoliative dermatitis due to iodine by Bordley, Harvey, and Howard.1 Randolph and Rollins2 reported temporary beneficial results in two cases of atopic dermatitis treated with corticotropin. Conn3 reported beneficial results in a case of giant urticaria due to food sensitivity. Gordon4 reported a dramatic clinical response in a case of urticaria and angioneurotic edema treated with corticotropin. Medical summaries on the use of corticotropin and cortisone, as well as commercial pamphlets on these products, frequently refer to the beneficial effects of corticotropin or cortisone in allergic dermatoses, although they rarely mention specific cases.
This report concerns 27 cases of urticaria and other allergic dermatoses treated with corticotropin and cortisone. The 27 cases reported are those of white male service and veteran patients hospitalized at the
EKBLAD GH. TREATMENT OF URTICARIA AND DERMATITIS VENENATA WITH CORTICOTROPIN (ACTH) AND CORTISONE. AMA Arch Derm Syphilol. 1951;64(5):628–634. doi:10.1001/archderm.1951.01570110098014