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Lupus Erythematosus (Treated with Quinacrine Hydrochloride [Atabrine Dihydrochloride]). Presented by Dr. George M. Lewis, for Dr. Donald Brooking.
M. M., a 46-year-old white housewife, was first seen on Aug. 21, 1951. She stated that approximately two years previously she had noted the presence of a red pea-sized nodule just below the bridge of her nose. The lesion persisted and would become aggravated upon exposure to sunlight. The patient was treated for several months with liver injections, penicillin injections, oral sulfonamide tablets, and vitamin B12. There was little change in the skin lesion. The patient also complained of dizziness, weakness, and fever. Later, she was given a short course of bismuth injections, but these were discontinued when she complained of pain. Shortly before she was seen in the skin clinic, a swelling of the left knee joint developed which was diagnosed as arthritis and treated with salicylates.
Sulzberger MH, Miller JL. NEW YORK ACADEMY OF MEDICINE, SECTION OF DERMATOLOGY AND SYPHILIS. AMA Arch Derm Syphilol. 1953;68(3):351–355. doi:10.1001/archderm.1953.01540090113021