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IT IS A PRINCIPLE of pathology that intermittent pressure produces hypertrophy and constant pressure atrophy. The application of pressure bandages to the nodules of xanthoma tuberosum will gradually bring about their regression. On the other hand, prolonged passive congestion may lead, under certain circumstances, to the development of new xanthomatous nodules.
Case 1.—M. F. B., a white man of 46, who is the proprietor of a gasoline service station, first consulted me on March 7, 1950. He stated that his skin trouble had begun in the fall of 1943. A low-fat diet, insulin, and dried thyroid gland had failed to produce any material change in his condition. No other member of his family had similar skin changes; since his relatives lived in scattered parts of the United States, they were not available for examination.
The patient's skin exhibited yellow, orange, and slightly violaceous round nodules and mush
BUTTERWORTH T. INFLUENCE OF PRESSURE ON NODULES OF XANTHOMA TUBEROSUM. AMA Arch Derm Syphilol. 1953;68(5):545–548. doi:10.1001/archderm.1953.01540110067009