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Article
November 1953

INFLUENCE OF PRESSURE ON NODULES OF XANTHOMA TUBEROSUM

Author Affiliations

READING, PA.

From the Department of Dermatology, Graduate School of Medicine, University of Pennsylvania (Herman Beerman, M.D., Chairman) and the Department of Dermatology, The Reading Hospital (Thomas Butterworth, M.D., Chief).

AMA Arch Derm Syphilol. 1953;68(5):545-548. doi:10.1001/archderm.1953.01540110067009

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Abstract

IT IS A PRINCIPLE of pathology that intermittent pressure produces hypertrophy and constant pressure atrophy. The application of pressure bandages to the nodules of xanthoma tuberosum will gradually bring about their regression. On the other hand, prolonged passive congestion may lead, under certain circumstances, to the development of new xanthomatous nodules.

CASE REPORTS

Case 1.—M. F. B., a white man of 46, who is the proprietor of a gasoline service station, first consulted me on March 7, 1950. He stated that his skin trouble had begun in the fall of 1943. A low-fat diet, insulin, and dried thyroid gland had failed to produce any material change in his condition. No other member of his family had similar skin changes; since his relatives lived in scattered parts of the United States, they were not available for examination.

The patient's skin exhibited yellow, orange, and slightly violaceous round nodules and mush

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