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March 1958

A Clinicopathologic Study of the Skin in Mongolism

Author Affiliations

Milwaukee; Paris

From the Department of Dermatology, Marquette University School of Medicine, and the Wisconsin Psychiatric Institute, University of Wisconsin. Associate Professor of Dermatology, Marquette University (Dr. Kersting); Professor, French School of Anthropology, Paris, at present Project Associate, Wisconsin Psychiatric Institute (Dr. Rapaport).

AMA Arch Derm. 1958;77(3):319-323. doi:10.1001/archderm.1958.01560030065010


The dermatological aspects observed in different conditions associated with mental deficiency have been emphasized by Touraine (1947).1 Recently Zeligman and Scalia (1954)2 surveyed a large number of Mongoloid patients and noticed the very high frequency of (1) protruding and/or fissured lower lip (100%), (2) scrotal or enlarged tongue (95%), (3) acrocyanosis (90%), and (4) a high incidence of xerosis or ichthyosis (69%). Ewing (1955-1956),3 studying the skin condition in a group of mentally defective patients, showed a significantly high incidence of dyskeratoses in Mongolism. Using the concept of dyskeratosis in a broad sense, Ewing classified under this term the following conditions: ichthyosis vulgaris, ichthyosis congenita (congenital ichthyosiform erythroderma), Darier's disease (keratosis follicularis), and tylosis palmaris et plantaris (keratosis or ichthyosis palmaris et plantaris). He reported that 18 of 36 Mongoloid patients included in his group of mental deficients presented dermatological manifestations classified

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