At times multiple-ingredient preparations have been depicted in an unfavorable light. However, we are becoming increasingly aware that few disorders have but a single facet. It is proper, therefore, where effective agents exist for each of the causes or manifestations of a disease that they all be used for speedier relief and cure. This is particularly true in cutaneous pathology where one can incorporate several ingredients in a common carrier for local application. This is eminently exemplified in the recently formulated preparation chymotrypsin (Chymar ointment), which combines three separate modern drugs, each serving its own specific purpose.
Composition and Action
Chymar ointment combines corticoid, antibiotic and proteolytic materials. The corticoid material, hydrocortamate hydrochloride, a solubilized form of hydrocortisone, has anti-inflammatory activity, reduces swelling, and allays itching. It is free from objectional systemic effects and does not interfere with wound healing.The antibiotic component, neomycin, is effective against both Gram-positive and
CORNBLEET T, CHESROW EJ. Topical Use of Chymar Ointment. Arch Dermatol. 1960;82(2):261–262. doi:10.1001/archderm.1960.01580020103020