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Case for Diagnosis: Granuloma Faciale; Lymphoma; Plasmocytoma? Presented by Dr. Ernst Rosenbaum and Dr. Murray Kahn (by invitation).
A 49-year-old white woman presented herself for hair loss of 15 years' duration and paronychial swelling of 12 years' duration. On physical examination 2 discrete, erythematous, smooth, split-peasized, infiltrated nodules were noted as incidental findings on the left cheek. The patient stated that they appeared but 1 week ago.A biopsy was taken from one of the nodules. The histologic picture was that of a cellular infiltrate around blood vessels and hair follicles of large reticular cells, lymphocytes, eosinophils, histiocytes, and plasma cells. The plasma cells made up 50% of the composition. Special stains failed to reveal mast cells.Under treatment with topical adrenocorticosteroid, regression has occurred.
Dr. Morris Leider: Extramedullary plasmocytosis may be an expression of overt or covert multiple myeloma or a forme fruste of that condition. This patient
Fisher AA, Silver H, Leider M. THE BRONX DERMATOLOGICAL SOCIETY. Arch Dermatol. 1962;86(3):345–348. doi:10.1001/archderm.1962.01590090087020