The case history of a 47-year-old male patient with vitiligo and hemochromatosis is reported. Skin biopsies disclose the uniform distribution of iron pigmentation, although the vitiligo spots seem to be deficient in melanin as opposed to the dark-colored skin areas where contents of melanin apparently have increased. The findings indicate that the pigmentation in hemochromatosis is due exclusively to an increased content of melanin.
PERDRUP A, POULSEN H. Hemochromatosis and Vitiligo. Arch Dermatol. 1964;90(1):34–37. doi:10.1001/archderm.1964.01600010040010