The occurrence of blisters on the skin of infants with certain disorders which are not usually associated with bullae in older persons is a well-recognized, but poorly understood phenomenon. In the present investigation the morphology of the epidermal-dermal basement membrane and its immediate environs, where many of these bullae arise, was examined in various age groups in a search for clues which might conceivably aid in explaining this blister-prone tendency of young skin.
CAWLEY EP, HSU YT, WEARY PE. Blisters and the Basement Membrane in Relation to Age. Arch Dermatol. 1966;93(3):367–368. doi:10.1001/archderm.1966.01600210103021