Ephidrosis, or local hyperhidrosis, in a 12-year-old girl is described. The profuse sweating was sharply limited to an area on the lateral aspect of one forearm. Hyperhidrosis was evoked by emotional stress and high environmental temperature. Sweating was normal in all other areas. The biopsy revealed an increased number of eccrine glands but no abnormality of sebaceous glands was noted; neither hypertrichosis nor comedones were seen. Systemic anticholinergics, tranquilizers, and sedatives, as well as topical anticholinergics afforded only partial or temporary relief of the very disturbing profuse sweating.
Goldstein N. Ephidrosis (Local Hyperhidrosis) Nevus Sudoriferous. Arch Dermatol. 1967;96(1):67-68. doi:10.1001/archderm.1967.01610010073012