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Article
July 1967

DETROIT DERMATOLOGICAL SOCIETY

Arch Dermatol. 1967;96(1):106-108. doi:10.1001/archderm.1967.01610010112020

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Abstract

Lichen Sclerosus et Atrophicus and Morphea. Presented by Dr. J. Grekin, and Dr. O. Schwartz.  A 60-year-old Negro woman first developed hardening of the skin of the upper left thigh associated with local pain and tenderness some nine years before this presentation. Similar lesions appeared over the trunk and extremities over the next 15 months. She was then admitted to the University Hospital in Ann Arbor, Mich, and results of a biopsy of one of the sites were reported as "consistent with scleroderma." The esophogram was not conclusive for atonic changes. Therapy with ethylenediaminetetraacetic acid (EDTA) on two occasions, 15 days each period, plus nicotinic acid, and pyridoxine gave uncertain improvement. Local tenderness and pain recurred in late 1965. Hypopigmented macules developed in the past few years.Physical examination revealed multiple, discrete- to confluent-indurated, hyperpigmented plaques on the extremities and trunk. Separately and in many plaques were found hypopigmented atrophic

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