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Blue Rubber Bleb Nevus. Presented by Anthony N. Domonkos, MD.
A 4½-year-old Negro girl has had a slightly swollen right knee since birth. On the inner portion of the knee are five elevated hyperpigmented and slightly verrucous angiomatous-appearing lesions. These are 1 to 2 cm in diameter. They itch and are slightly painful. Her mother notes that at times beads of perspiration appear over the dusky lesions. No other members of the immediate family have similar lesions except this child's maternal uncle.
A biopsy specimen of the lesion revealed the following: a slightly thickened epidermis; in the mid and lower dermis, dilated vessels, surrounded by strands of smooth muscles and numerous sweat glands.
Lewis Shapiro, MD: I have no previous personal experience with this condition, but I have reviewed the literature. From a clinical point of view, these are not blebs; they are
NEW YORK DERMATOLOGICAL SOCIETY. Arch Dermatol. 1967;96(2):214-217. doi:10.1001/archderm.1967.01610020106032