[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address Please contact the publisher to request reinstatement.
[Skip to Content Landing]
October 1967

Methotrexate in PsoriasisPrecipitation of Gout

Author Affiliations


From the departments of rheumatology (Dr. Martin and Mr. Wallace) and dermatology (Dr. Gordon), Temple University Health Sciences Center, Philadelphia.

Arch Dermatol. 1967;96(4):431-433. doi:10.1001/archderm.1967.01610040081015

Two psoriatic patients are reported with hyperuricemia and gout who had an episode of acute gouty arthritis within 24 hours after the administration of methotrexate intravenously.

A patient with gout and psoriasis, in which treatment with methotrexate is contemplated should probably receive prophylactic colchicine to prevent the precipitation of gouty attacks.