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Article
October 1967

Methotrexate in PsoriasisPrecipitation of Gout

Author Affiliations

Philadelphia

From the departments of rheumatology (Dr. Martin and Mr. Wallace) and dermatology (Dr. Gordon), Temple University Health Sciences Center, Philadelphia.

Arch Dermatol. 1967;96(4):431-433. doi:10.1001/archderm.1967.01610040081015
Abstract

Two psoriatic patients are reported with hyperuricemia and gout who had an episode of acute gouty arthritis within 24 hours after the administration of methotrexate intravenously.

A patient with gout and psoriasis, in which treatment with methotrexate is contemplated should probably receive prophylactic colchicine to prevent the precipitation of gouty attacks.

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