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December 1967

Calcinosis Cutis Following Intralesional Injection of Triamcinolone Hexacetonide

Author Affiliations


From the departments of dermatology (Dr. Baden) and orthopedic research (Dr. Bonar), Harvard Medical School and the Massachusetts General Hospital, Boston.

Arch Dermatol. 1967;96(6):689-691. doi:10.1001/archderm.1967.01610060083014

Calcinosis cutis was observed in a patient with nummular eczema following the intralesional injection of triamcinolone hexacetonide. X-ray diffraction analysis indicated that the calcium was deposited as hydroxyapatite crystals. Following decalcification of a deposit, an x-ray diffraction pattern was obtained which was similar to the original steroid. This suggested that the calcified deposit contained a steroid derived from the triamcinolone hexacetonide.