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January 1968


Arch Dermatol. 1968;97(1):90-94. doi:10.1001/archderm.1968.01610070096016

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Erythema Multiforme Bullosum. Presented by Dr. Carl T. Nelson.  A Negro woman, age 41 years, has had recurrent bullous erythema multiforme for the past 18 years. This has waxed and waned, never clearing entirely, except during a pregnancy in 1962-1963. Six months after the birth of the child, however, the eruption recurred and has been present since.The patient was admitted to University Hospital in 1959 for three weeks but no cause for the condition was found. There has never been any known relationship to drug intake, focal infection, or intercurrent infection.

Description.—  There is generalized erythema multiforme on the trunk and extremities with many areas of hyperpigmentation. In some areas, residual blebs are seen.

Laboratory.—  No recent laboratory studies have been done. There has been no recent biopsy.

Course and Treatment.—  Because of the history of remission during and shortly after pregnancy in 1962-1963, the patient was given ethinyl

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