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July 1968

Penicillamine for Scleroderma

Author Affiliations

Miami, Fla

From the Department of Dermatology, University of Miami School of Medicine, Miami, Fla.

Arch Dermatol. 1968;98(1):51-52. doi:10.1001/archderm.1968.01610130057012

Five patients with advanced systemic scleroderma were treated with high doses of D-penicillamine for periods up to 11 months. Careful measurement of mobility of involved joints before and after therapy revealed no improvement. Side effects occurred in all patients.