Anticoagulant drugs are frequently used in the management of a variety of medical disorders. The common cutaneous side effects due to excessive lowering of the prothrombin level are well known. In recent years hemorrhagic necrosis of the skin due to anticoagulants has been recognized. However, there is still another type of side effect of which the physician using anticoagulant therapy should be aware; maculopapular purpuric or vesicular lesions. We report four patients with this type of eruption.
Schiff BL, Kern AB. Cutaneous Reactions to Anticoagulants. Arch Dermatol. 1968;98(2):136-137. doi:10.1001/archderm.1968.01610140034006