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Epidermoid Carcinoma, Adenoacanthoma Type. Presented by Anthony N. Domonkos, MD.
This 36-year-old white man was seen in August 1967 for a rapidly growing lesion present for a month on his left pectoral area. A biopsy was reported as keratoacanthoma by a general pathologist. The lesion was removed, but recurred a few weeks later. It was removed again in September and three x-ray exposures of 500 rads were given for a total of 1,500 rads. Despite this treatment the lesion continued to grow. On the left pectoral area was a 5-cm wide fungating tumor, elevated about 1 cm. No adenopathy was or had been present. A biopsy of the lesion, reported by Dr. Lewis Shapiro, revealed the epidermis to be absent over most of the specimen. At one edge the epidermis was acanthotic, covered by parakeratotic crusted horn and forming a lip. Within the cutis were proliferating strands of atypical prickle
THE NEW YORK DERMATOLOGICAL SOCIETY. Arch Dermatol. 1969;99(3):366-370. doi:10.1001/archderm.1969.01610210120025