Compilation of data found in the literature on benign melanocytic nevi of the oral mucosa and that of six cases previously unreported show that nevi in this location are not rare and may be more common than previously thought. A total of 44 are available for study. Nevi of the intradermal type are the most common and are usually nodules or polypoid lesions which may have a smooth or rough surface, and may or may not be pigmented. Nevi are most commonly found on the palate and are more common in females than males. They are diagnosed usually in people in the fourth and fifth decade, but have been reported in the very young or very old. Differential diagnosis of other intra-oral lesions with a similar appearance are discussed. The malignant potential of oral mucosal nevi is unknown but is probably similar to those of the skin. However, any melanocytic lesion in the mouth should be removed. Nevi should be considered in the differential diagnosis of lesions of the oral mucosa.
Weathers DR. Benign Nevi of the Oral MucosaA Report of Six Cases. Arch Dermatol. 1969;99(6):688-692. doi:10.1001/archderm.1969.01610240046007