A child with congenital unilateral ichthyosiform erythroderma is described. There is marked hypoplasia and aplasia of bony structures and the brain on the same side as the skin involvement. A teratogenic effect is suggested, but not proven. The constellation of signs and symptoms in this patient is so similar to that of the patient reported by Rossman and associates that the existence of a distinctive clinical entity is suggested.
Cullen SI, Harris DE, Carter CH, Reed WB. Congenital Unilateral Ichthyosiform Erythroderma. Arch Dermatol. 1969;99(6):724-729. doi:10.1001/archderm.1969.01610240082015