A patient is reported with a recurrent skin eruption which suggested a reticulosis, lichen planus, or pityriasis lichenoides varioliformis of Mucha Haberman. Serological and immunological tests for toxoplasmosis were repeatedly positive which led us to postulate that the skin eruption is a nonspecific allergic reaction. Treatment with pyrimethamine (Daraprim) brought prompt improvement in the skin changes, as well as in the general condition.
Andreev VC, Angelov N, Zlatkov NB. Skin Manifestations in Toxoplasmosis. Arch Dermatol. 1969;100(2):196-199. doi:10.1001/archderm.1969.01610260072013