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August 1969


Arch Dermatol. 1969;100(2):245-250. doi:10.1001/archderm.1969.01610260121023

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Pachyonychia Congenita. Presented by the Department of Dermatology Staff of the Detroit General Hospital.  A 22-year-old Negro man has had deformed nails since birth. During infancy and early childhood he developed lesions of the glabrous skin and buccal mucosa. He has been able to use his hands well despite the deformed nails. The family history is negative. He has been in good health and is of average intelligence. The nails have been repeatedly traumatized, with resultant paronychia and loss of individual nails.Examination showed all 20 nails to be similarly affected. The nails are thick, smooth, and shiny. The nail plate is of normal thickness and consistency, but is pushed upward by hard keratinous material collecting under it so that the distal two thirds of the dorsal surface of the nail forms a 30 to 40° angle with the axis of the phalanx. On the hands, knees, elbows, waist, buttocks,

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