A sarcoidal reaction in a tattoo may be an isolated finding or it may represent a cutaneous sign of systemic disease. Two cases of systemic sarcoidosis with granulomatous reactions in tattoos are reported. In each the presenting complaint was the development of a nodule within a tattoo of many years duration. The diagnosis was suspected when histological examination of an intracutaneous nodule revealed a granulomatous reaction of the sarcoidal type. Further studies such as biopsy of lymph nodes, chest x-ray films, and culture studies established the diagnosis. The need for complete evaluation of patients with sarcoidal reactions in tattoos is stressed.
Dickinson JA. Sarcoidal Reactions in Tattoos. Arch Dermatol. 1969;100(3):315-319. doi:10.1001/archderm.1969.01610270057013