Both occlusive tape alone and steroid incorporated into an occlusive tape will cause inhibition of enzyme activities in the lesions of psoriasis as well as in the normal-appearing skin. The steroid tape is more effective than the tape alone in producing these effects.
Halprin KM, Fukui K, Ohkawara A. Flurandrenolone (Cordran) Tape and Carbohydrate Metabolizing EnzymesUse in the Epidermis of People With Psoriasis. Arch Dermatol. 1969;100(3):336-341. doi:10.1001/archderm.1969.01610270078018