We report a patient with osteopoikilosis and dermatofibrosis lenticularis disseminata with unusual flexural location. The patient was undersized, had diabetes mellitus, and pronounced arteriosclerotic changes. Histologic examination showed the cutaneous lesions sharply demarcated with a pseudotumorous appearance. Electron microscopic studies of these lesions revealed some of the elastic fibers broken up, partly into big lumps consisting of the amorphous component, partly into smaller granular elements, presumably representing the fibrillar component. The collagen fibers were normal. A certain resemblance to pseudoxanthoma elasticum is discussed.
Danielsen L, Midtgaard K, Christensen HE. Osteopoikilosis Associated With Dermatofibrosis Lenticularis Disseminata. Arch Dermatol. 1969;100(4):465-470. doi:10.1001/archderm.1969.01610280083016