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November 1969


Arch Dermatol. 1969;100(5):640-654. doi:10.1001/archderm.1969.01610290124030

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Epidermolytic Hyperkeratosis. Presented by Douglas Torre, MD.  This 5-year-old white boy was delivered spontaneously, three weeks prematurely, and showed generalized redness of his skin. He remained in the hospital until 5½ months of age because of his dermatitis and failure to thrive, rating below the third percentile for weight and in the tenth percentile for length. The redness of his skin persisted, as well as a tendency to "come away in sheets" with even the gentlest handling, and the occasional formation of large blisters. The eruption has been worse during the summer. Appetite and weight gain have been poor. Retardation of motor development has been attributed to severity of skin involvement of hands and feet. The teeth began to erupt at 12 months but crumbled away to the gingival margins by age 2.The family history is negative for related skin disorder. The patient has two unaffected brothers and one

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