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December 1969

Variable ErythrokeratodermaAn Unusual Case

Author Affiliations


From the First Department of Dermatology, University of Vienna, School of Medicine, Vienna.

Arch Dermatol. 1969;100(6):744-748. doi:10.1001/archderm.1969.01610300094017

A patient is presented with an unusual type of variable erythrokeratoderma exhibiting a unique combination of features: Onset at birth with generalized erythroderma; successive development of figurate variable erythemas involving the entire skin; diffuse universal hyperkeratosis including palms and soles and, in addition, massive patchy hyperkeratotic lesions of unusual extent; and a distinct histopathological picture. Enzyme-histochemical studies were performed. The classification of variable erythrokeratodermas is discussed.