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January 1970

Scleredema Adultorum of Buschke and Diabetes Mellitus

Author Affiliations

Chapel Hill, NC

From the Division of Dermatology, Department of Medicine, University of North Carolina Medical School, Chapel Hill.

Arch Dermatol. 1970;101(1):27-35. doi:10.1001/archderm.1970.04000010029004

Three patients with long-standing, severe, complicated diabetes mellitus developed skin changes of scleredema adultorum of Buschke. The scleredema showed no tendency to resolve. Acid mucopolysaccharides were demonstrated histochemically in the dermis. The possibility is discussed that there may be some association between diabetes mellitus and scleredema.