Seven cases of a solitary tumor, with the histopathologic feature of granular degeneration, were identified as isolated epidermolytic acanthoma. Clinically the lesion is not diagnostic, but resembles a wart. It is apparently not heritable, although it shows the same microscopic features as the dominantly inherited dermatoses recently termed epidermolytic hyperkeratosis.
Shapiro L, Baraf CS. Isolated Epidermolytic AcanthomaA Solitary Tumor Showing Granular Degeneration. Arch Dermatol. 1970;101(2):220-223. doi:10.1001/archderm.1970.04000020090014