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Article
March 1970

Milker's NoduleA Clinical and Electron Microscopic Report

Author Affiliations

USAF; Miami, Fla

From the Department of Dermatology, University of Miami School of Medicine, and the Dermatology Service, Veterans Administration Hospital, Miami, Fla.

Arch Dermatol. 1970;101(3):305-311. doi:10.1001/archderm.1970.04000030049007
Abstract

The clinical application of electron microscopy for the rapid diagnosis of viral infections is illustrated by two human and three bovine cases of milker's nodules. The virus was present in both crusts and biopsy material from quite different clinical lesions. A provisional diagnosis was available within one hour. Since preservatives or refrigeration are not necessary, crusts and dried vesicle fluid of suspected lesions of herpes or poxvirus infections can be mailed to a distant electron microscopic facility, providing a quick, practical method for the identification of distinct viral groups.

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