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Article
April 1970

NETHERTON'S SYNDROME AND ICHTHYOSIS LINEARIS CIRCUMFLEXA

Author Affiliations

35 E 84th St New York 10028

Arch Dermatol. 1970;101(4):485. doi:10.1001/archderm.1970.04000040107024
Abstract

To the Editor.—  Altman and Stroud,1 recently reported on two patients with typical features of both ichthyosis linearis circumflexa and Netherton's syndrome. In 1962 I presented a 22-year-old Negro woman with ichthyosis serpentina, bamboo hair, periodic loss of scalp, axillary, and pubic hair, atopic eczema, pulmonary tuberculosis, and asthma.2 A 2-year-old sister (among seven normal siblings) had begun to show broken hair shafts. Ichthyosis serpentina, a mild form of ichthyosis vulgaris, therefore, seems to be another variant—not necessarily psoriasiform—of ichthyosis associated with trichorrhexis invaginata (bamboo hair). Since atopy has been present in some of the reported cases but has been missing in others, this component does not seem to be a necessary part of the syndrome.

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