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June 1970

Topical Unresponsiveness of Depigmented Areas

Author Affiliations


From the Division of Dermatology, University of Colorado Medical Center, Denver.

Arch Dermatol. 1970;101(6):662-663. doi:10.1001/archderm.1970.04000060034008

Two patients failed to show erythema from topical-contact sensitization in areas depigmented by para-tertiary butylphenol. However, the depigmented areas responded with erythema to both mumps skin test antigen and histamine phosphate administered intradermally. No cause could be determined for the topical unresponsiveness of the depigmented areas; a lack of response to contact sensitization was not seen in patients with vitiligo.