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To the Editor.—
There are only 50 cases of Kyrle's disease reported in the literature since 1916. Only 20 of them are accepted as true Kyrle, one third of them with diabetes, congestive heart failure, and/or nephrosclerosis. We are reporting a case which fulfills all the requirements of Kyrle's disease.
Report of a Case.—
A 54-year-old Negro man with a 17-year history of diabetes mellitus was hospitalized several times since 1964 for severe hypertension, chronic bronchitis and pulmonary emphysema, nephrosclerosis with renal failure (uremia), congestive heart failure, and gastrointestinal bleeding secondary to uremia.During a hospital admission in 1964, the patient complained of severe generalized pruritus. Shortly thereafter, he developed a papular eruption on his legs which spread to his arms and body. The lesion was papular in character; the papules varied in size from 1 to 5 mm in diameter located on the arms, elbows, knees, legs, and toes.
Ephraim AJ, Barbanti BJ. KYRLE'S DISEASE. Arch Dermatol. 1970;101(6):704-705. doi:10.1001/archderm.1970.04000060076022