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July 1970

North American Blastomycosis Presenting as an Acute Panniculitis and Arthritis

Author Affiliations

USAF, Philadelphia; USAF, Washington, DC

From the Department of Dermatology, USAF Hospital Keesler, Keesler Air Force Base, Miss. Maj Maioriello is now with Thomas Jefferson University Hospital, Philadelphia, and Lt Col Merwin is with USAF Hospital, Andrews Air Force Base, Washington, DC.

Arch Dermatol. 1970;102(1):92-96. doi:10.1001/archderm.1970.04000070094014

A 58-year-old Negro diabetic woman presented with short-term panniculitis and suppurative arthritis. This case was a difficult diagnostic problem until isolation and identification of Blastomyces dermatitidis was accomplished by culture of the knee-joint fluid and an excised subcutaneous skin nodule. The clinical and histopathologic appearance of the short-term and resolved lesions of this unusual presentation are described and compared with the classic skin lesions of North American blastomycosis. An 11-week course of therapy with amphotericin B resulted in an apparent cure.