To the Editor.—
In the Case Report "Fixed Drug Eruption Due to Tetracycline" Minkin et al (Arch Derm100:749, 1969) state that their patient is the second reported case of fixed-drug eruption due to tetracycline.They cited the case reported by Welsh1 but overlooked two others2,3 reported in the Archives. I have recently reported another patient.4Their discussion also omitted mention of Ninomiya's5 report of fixed-drug eruption due to oxytetracycline.That it is probably the parent tetracycline compound which is actually responsible for producing the eruption is indicated by Welsh's1,6,7 series of papers and Dougherty's8 in which single patients were shown to cross-react to chlortetracycline, oxytetracycline, and tetracycline.
Tarnowski WM. FIXED-DRUG ERUPTION DUE TO TETRACYCLINE. Arch Dermatol. 1970;102(2):234. doi:10.1001/archderm.1970.04000080106026