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Article
September 1970

Histopathologic Concept of Epidermolytic Hyperkeratosis

Author Affiliations

Miami, Fla

From the Department of Dermatology, University of Miami (Fla) School of Medicine.

Arch Dermatol. 1970;102(3):253-259. doi:10.1001/archderm.1970.04000090015003
Abstract

Epidermolytic hyperkeratosis (EH) is a distinctive histologic expression of an epithelial pathologic process. The characteristic histopathologic features appear in a variety of acquired and congenital skin lesions. They range from focal EH confined to a single rete ridge, that is clinically unapparent, to widespread EH that is manifested clinically as bullous congenital ichthyosiform erythroderma. Microscopic examination enables detection of EH beneath an array of clinical masquerades.

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