The distribution of glycogen was studied in preparations for light and electron microscopy of nine surgical specimens of clinical leukoplakia in normally nonkeratinized parts of human oral mucosa and in two clinically normal areas of buccal mucosa. Overall ratings of tissue content of glycogen in electron microscopic and light microscopic preparations were in good agreement. The glycogen content of the epithelium of the nine lesions was found to be unrelated to the degree of inflammation present and to be inversely related to the degree of keratinization. No exception was found at the cellular level to an inverse relation between the content of glycogen and the degree of keratinization.
Plackova A, Waterhouse JP, Meyer J. Glycogen in Clinical LeukoplakiaDistribution and Fine Structure in Human Buccal Mucosa. Arch Dermatol. 1970;102(3):291-299. doi:10.1001/archderm.1970.04000090053008