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September 1970

Pemphigus and Herpes SimplexAntibody Response to Corticosteroids in a Patient

Author Affiliations

Miami, Fla

From the departments of dermatology (Drs. Indgin and Katz) and pediatrics (Dr. Connor), University of Miami (Fla) School of Medicine. Dr. Katz is now with the Department of Dermatology, Walter Reed General Hospital, Washington DC, and Dr. Connor is with the Department of Pediatrics, University of California, San Diego School of Medicine, La Jolla.

Arch Dermatol. 1970;102(3):333-336. doi:10.1001/archderm.1970.04000090095017

Pemphigus occurred in a patient who developed a generalized recurrent herpes simplex infection while being treated with very large doses of orally administered prednisone. A disparity between herpesvirus hominis antibodies, antiepithelial antibodies, and total immunoglobulins was observed. There is no good evidence showing that corticosteroids have an adverse effect on recurrent herpes simplex infection of the skin.